Hoodia Gordonii

How does Hoodia work?

The appetite suppressant effects of Hoodia were first observed in 1937 by a Dutch anthropologist studying the primitive San Bushmen of the Kalahari Desert. It was noticed that the nomadic Bushmen, (who call it Xhoba) ate the stem of the Hoodia plant to stave off hunger during long hunting trips in the sparsely vegetated area. The active ingredient in Hoodia is the appetite-suppressing molecule, P57, which is licensed to the British pharmaceutical company Phytopharm who are researching its potential as an anti-obesity drug.

Scientists from Phytopharm say P57 acts on the brain in a manner similar to glucose. It tricks the brain into thinking you are full even when you have not eaten, reduces interest in food and delays the time before hunger sets in.

Hoodia Gordonii


Chemical fingerprint of Hoodia species, dietary supplements, and related genera by using HPTLC
Journal of Separation Science
Volume 31, Issue 22, Date: December 2008, Pages: 3959-3964
Chidananda Swamy Rumalla, Bharathi Avula, Yatin J. Shukla, Yan-Hong Wang, Rahul S. Pawar, Troy J. Smillie, Ikhlas A. Khan

Identification and structural characterization of steroidal glycosides in Hoodia gordonii by ion-trap tandem mass spectrometry and liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry
Rapid Communications in Mass Spectrometry
Volume 22, Issue 16, Date: 30 August 2008, Pages: 2587-2596
Bharathi Avula, Yan-Hong Wang, Rahul S. Pawar, Yatin J. Shukla, Troy J. Smillie, Ikhlas A. Khan

On the Genus Hoodia, with a Diagnosis of a New Species.
Journal of the Linnean Society of London, Botany
Volume 15, Issue 84, Date: July 1876, Pages: 248-252
W. T. Thiselton Dyer
X. On the genera Liothrips and Hoodia.

Transactions of the Royal Entomological Society of London
Volume 60, Issue 2, Date: October 1912, Pages: 470-476
H. Karny, G. A. Elliott, R. S. Bagnall

Topical application of a plant extract to different life stages of Trichoplusia ni fails to influence feeding or oviposition behaviour
Entomologia Experimentalis et Applicata
Volume 132, Issue 3, Date: September 2009, Pages: 275-282
Yasmin Akhtar, Ikkei Shikano, Murray B. Isman

Plate 479. Hoodia Pilifera subsp. Pillansii Apocynaceae: Asclepiadoideae
Curtis's Botanical Magazine
Volume 20, Issue 4, Date: November 2003, Pages: 219-224
Robert H. Archer, Janine E. Victor

Rhetoric, Realism and Benefit-Sharing of Hoodia
Journal of World Intellectual Property
Volume 7, Issue 6, Date: November 2004, Pages: 851-876
Rachel Wynberg

Quantitative liquid chromatography/time-of-flight mass spectrometry Hoodia
Biomedical Chromatography
Volume 21, Issue 6, Date: June 2007, Pages: 567-576
Leah N. Williamson, Michael G. Bartlett

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